Avenaciolide

Cat. No.: HY-N10272: FAQs
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Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation.

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Avenaciolide Chemical Structure

CAS No. : 26057-70-5

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Description	Avenaciolide is an antifungal bis-γ-lactone found in Aspergillus avenaceus. Avenaciolide has also antibacterial action. Avenaciolide is a specific inhibitor of glutamate transport in rat liver mitochondria. Avenaciolide interferes with the ability of ADP to stimulate the rate of glutamate oxidation^[1]^[2].
Molecular Weight	266.33
Formula	C₁₅H₂₂O₄
CAS No.	26057-70-5
SMILES	CCCCCCCC[C@H]1[C@@]2([H])[C@@](OC(C2=C)=O)([H])C(O1)=O
Structure Classification	Others
Initial Source	Microorganisms Aspergillus avenaceaus
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Castelo-Branco PA, et al. Synthesis and antifungal activity of aromatic bis-gamma-lactones analogous to avenaciolide. Chem Biodivers. 2007;4(12):2745-2754. [Content Brief] [2]. McGivan JD, Chappell JB. Avenaciolide: a specific inhibitor of glutamate transport in rat liver mitochondria. Biochem J. 1970;116(4):37P-38P. [Content Brief]

Avenaciolide Related Classifications

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	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avenaciolide26057-70-5FungalBacterialantifungalantibacterial actionglutamate transportADPInhibitorinhibitorinhibit

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Avenaciolide

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