2. Immunology/Inflammation
  3. Interleukin Related
  4. Avizakimab

Avizakimab  (Synonyms: BOS161721)

Cat. No.: HY-P99451 Purity: 99.35%
COA

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Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21.

For research use only. We do not sell to patients.

CAS No. : 2229685-51-0

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Based on 1 publication(s) in Google Scholar

Avizakimab Related Antibodies

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View All Interleukin Related Isoform Specific Products:

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Description

Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Humanized
In Vitro

Avizakimab (BOS161721) prevents IL-21 binding to the IL-21 receptor (IL-21R) and inhibits bioactivity[1].
Avizakimab inhibits the downstream signaling, plasma cell differentiation, and natural killer cell activation induced by IL-21 and suppressed antibody responses to keyhole limpet hemocyanin (KLH) antigen[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Avizakimab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Avizakimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation

Purity: 99.35%

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Avizakimab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avizakimab2229685-51-0BOS161721BOS 161721BOS-161721Interleukin RelatedILIL-21KLHkeyhole limpet hemocyaninInhibitorinhibitorinhibit

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