2. Protein Tyrosine Kinase/RTK
  3. TAM Receptor
  4. Axl-IN-6

Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model.

For research use only. We do not sell to patients.

Axl-IN-6 Chemical Structure

Axl-IN-6 Chemical Structure

CAS No. : 2642224-22-2

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Axl-IN-6 Related Antibodies

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Description

Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].

IC50 & Target

Axl

 

Molecular Weight

492.65

Formula

C32H36N4O
CAS No.
SMILES

CC(OC1=CC=C(C=C1)C2=CC=CC3=CN=C(N=C32)NC4=CC5=C(CC[C@@H](CC5)N6CCCC6)C=C4)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Axl-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axl-IN-62642224-22-2TAM ReceptorTyro3AxlMerMV-4-11 cellsICR miceOrally activeAntitumorInhibitorinhibitorinhibit

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HY-146615
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