AZD9496 deacrylic acid phenol

Cat. No.: HY-46340 Purity: 96.56%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

AZD9496 deacrylic acid phenol is a fragment of target protein ligand of PROTAC ER Degrader-4 (HY-135309).

For research use only. We do not sell to patients.

AZD9496 deacrylic acid phenol Chemical Structure

CAS No. : 2173404-70-9

Size	Price	Stock	Quantity
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 400	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 850	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1350	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1950	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

AZD9496 deacrylic acid phenol is a fragment of target protein ligand of PROTAC ER Degrader-4 (HY-135309)^[1].

Molecular Weight

388.43

Formula

C₂₂H₂₃F₃N₂O

CAS No.

2173404-70-9

Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(C)(F)CN1[C@@](C2=C(C=C(C=C2F)O)F)([H])C3=C(C[C@H]1C)C4=CC=CC=C4N3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (257.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5745 mL	12.8723 mL	25.7447 mL
5 mM	0.5149 mL	2.5745 mL	5.1489 mL
10 mM	0.2574 mL	1.2872 mL	2.5745 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.56%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (260 KB) HNMR (212 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5745 mL	12.8723 mL	25.7447 mL	64.3617 mL
	5 mM	0.5149 mL	2.5745 mL	5.1489 mL	12.8723 mL
	10 mM	0.2574 mL	1.2872 mL	2.5745 mL	6.4362 mL
	15 mM	0.1716 mL	0.8582 mL	1.7163 mL	4.2908 mL
	20 mM	0.1287 mL	0.6436 mL	1.2872 mL	3.2181 mL
	25 mM	0.1030 mL	0.5149 mL	1.0298 mL	2.5745 mL
	30 mM	0.0858 mL	0.4291 mL	0.8582 mL	2.1454 mL
	40 mM	0.0644 mL	0.3218 mL	0.6436 mL	1.6090 mL
	50 mM	0.0515 mL	0.2574 mL	0.5149 mL	1.2872 mL
	60 mM	0.0429 mL	0.2145 mL	0.4291 mL	1.0727 mL
	80 mM	0.0322 mL	0.1609 mL	0.3218 mL	0.8045 mL
	100 mM	0.0257 mL	0.1287 mL	0.2574 mL	0.6436 mL