1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Azelaic acid-d14

Azelaic acid-d14  (Synonyms: Nonanedioic acid-d14)

Cat. No.: HY-B0704S Purity: 99.63%
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Azelaic acid-d14 is the deuterium labeled Azelaic acid[1]. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners[2][3].

For research use only. We do not sell to patients.

Azelaic acid-d<sub>14</sub> Chemical Structure

Azelaic acid-d14 Chemical Structure

CAS No. : 119176-67-9

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Description

Azelaic acid-d14 is the deuterium labeled Azelaic acid[1]. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners[2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

202.31

Formula

C9H2D14O4

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to yellow

SMILES

OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (494.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9429 mL 24.7145 mL 49.4291 mL
5 mM 0.9886 mL 4.9429 mL 9.8858 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9429 mL 24.7145 mL 49.4291 mL 123.5727 mL
5 mM 0.9886 mL 4.9429 mL 9.8858 mL 24.7145 mL
10 mM 0.4943 mL 2.4715 mL 4.9429 mL 12.3573 mL
15 mM 0.3295 mL 1.6476 mL 3.2953 mL 8.2382 mL
20 mM 0.2471 mL 1.2357 mL 2.4715 mL 6.1786 mL
25 mM 0.1977 mL 0.9886 mL 1.9772 mL 4.9429 mL
30 mM 0.1648 mL 0.8238 mL 1.6476 mL 4.1191 mL
40 mM 0.1236 mL 0.6179 mL 1.2357 mL 3.0893 mL
50 mM 0.0989 mL 0.4943 mL 0.9886 mL 2.4715 mL
60 mM 0.0824 mL 0.4119 mL 0.8238 mL 2.0595 mL
80 mM 0.0618 mL 0.3089 mL 0.6179 mL 1.5447 mL
100 mM 0.0494 mL 0.2471 mL 0.4943 mL 1.2357 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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