Azide-A-DSBSO crosslinker

Cat. No.: HY-157414: FAQs
Data Sheet SDS Handling Instructions

Molarity Calculator

Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS).

For research use only. We do not sell to patients.

Azide-A-DSBSO crosslinker Chemical Structure

CAS No. : 1704097-02-8

Size	Price	Stock
5 mg	USD 180	Ask For Quote & Lead Time
10 mg	USD 290	Ask For Quote & Lead Time
25 mg	USD 580	Ask For Quote & Lead Time
50 mg	USD 930	Ask For Quote & Lead Time
100 mg	USD 1500	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

647.68

Formula

C₂₄H₃₃N₅O₁₂S₂

CAS No.

1704097-02-8

Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCCCC1(C)OCC(CS(CCC(ON2C(CCC2=O)=O)=O)=O)(CS(CCC(ON3C(CCC3=O)=O)=O)=O)CO1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (154.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5440 mL	7.7199 mL	15.4397 mL
5 mM	0.3088 mL	1.5440 mL	3.0879 mL
10 mM	0.1544 mL	0.7720 mL	1.5440 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Data Sheet (269 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. Matzinger M, et al. Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides. J Proteome Res. 2020 May 1;19(5):2071-2079. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5440 mL	7.7199 mL	15.4397 mL	38.5993 mL
	5 mM	0.3088 mL	1.5440 mL	3.0879 mL	7.7199 mL
	10 mM	0.1544 mL	0.7720 mL	1.5440 mL	3.8599 mL
	15 mM	0.1029 mL	0.5147 mL	1.0293 mL	2.5733 mL
	20 mM	0.0772 mL	0.3860 mL	0.7720 mL	1.9300 mL
	25 mM	0.0618 mL	0.3088 mL	0.6176 mL	1.5440 mL
	30 mM	0.0515 mL	0.2573 mL	0.5147 mL	1.2866 mL
	40 mM	0.0386 mL	0.1930 mL	0.3860 mL	0.9650 mL
	50 mM	0.0309 mL	0.1544 mL	0.3088 mL	0.7720 mL
	60 mM	0.0257 mL	0.1287 mL	0.2573 mL	0.6433 mL
	80 mM	0.0193 mL	0.0965 mL	0.1930 mL	0.4825 mL
	100 mM	0.0154 mL	0.0772 mL	0.1544 mL	0.3860 mL