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  4. Azide-A-DSBSO crosslinker

Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS).

For research use only. We do not sell to patients.

Azide-A-DSBSO crosslinker Chemical Structure

Azide-A-DSBSO crosslinker Chemical Structure

CAS No. : 1704097-02-8

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5 mg USD 110 Ask For Quote & Lead Time
10 mg USD 175 Ask For Quote & Lead Time
25 mg USD 340 Ask For Quote & Lead Time

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Azide-A-DSBSO crosslinker Related Antibodies

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Description

Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS)[1].

Molecular Weight

647.68

Formula

C24H33N5O12S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCCCC1(C)OCC(CS(CCC(ON2C(CCC2=O)=O)=O)=O)(CS(CCC(ON3C(CCC3=O)=O)=O)=O)CO1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (154.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5440 mL 7.7199 mL 15.4397 mL
5 mM 0.3088 mL 1.5440 mL 3.0879 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5440 mL 7.7199 mL 15.4397 mL 38.5993 mL
5 mM 0.3088 mL 1.5440 mL 3.0879 mL 7.7199 mL
10 mM 0.1544 mL 0.7720 mL 1.5440 mL 3.8599 mL
15 mM 0.1029 mL 0.5147 mL 1.0293 mL 2.5733 mL
20 mM 0.0772 mL 0.3860 mL 0.7720 mL 1.9300 mL
25 mM 0.0618 mL 0.3088 mL 0.6176 mL 1.5440 mL
30 mM 0.0515 mL 0.2573 mL 0.5147 mL 1.2866 mL
40 mM 0.0386 mL 0.1930 mL 0.3860 mL 0.9650 mL
50 mM 0.0309 mL 0.1544 mL 0.3088 mL 0.7720 mL
60 mM 0.0257 mL 0.1287 mL 0.2573 mL 0.6433 mL
80 mM 0.0193 mL 0.0965 mL 0.1930 mL 0.4825 mL
100 mM 0.0154 mL 0.0772 mL 0.1544 mL 0.3860 mL
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Azide-A-DSBSO crosslinker Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azide-A-DSBSO crosslinker1704097-02-8OthersMSXL-MSproteinpeptideazideDSBSOInhibitorinhibitorinhibit

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