2. Anti-infection
  3. Bacterial Antibiotic
  4. Bacitracin Zinc

Bacitracin Zinc  (Synonyms: Zinc bacitracin)

Cat. No.: HY-B0278 Purity: 98.76%
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Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle.

For research use only. We do not sell to patients.

Bacitracin Zinc Chemical Structure

Bacitracin Zinc Chemical Structure

CAS No. : 1405-89-6

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500 mg USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle[1][2].
In Vivo

Bacitracin Zinc (30 mg/kg; 6 weeks; p.o.) can improve the production performance and gut microbiota of broiler chickens attacked by Eimeria acervulina and Eimeria tenella[1].
Bacitracin Zinc (6.62 mg/kg; twice daily; 82 days; p.o.) can affect the production performance, hepatic gluconeogenesis, lipid metabolism, and intramuscular fat content of beef cattle[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Broilers challenged with Eimeria acervulina and Eimeria tenella[1].
Dosage: 30 mg/kg
Administration: Oral gavage (p.o.); 6 weeks
Result: Increased proliferation of beneficial clostridia in the small intestine of broiler chickens 7 days after Eimeria acervulina and Eimeria tenella attack, including Staphylococcus, Enterococcus, and Clostridium.
Animal Model: Nellore × Angus (F1) young bulls (n = 72; BW 368 ± 16.3 kg)[2].
Dosage: 6.62 mg/kg
Administration: Oral gavage (p.o.); twice daily; 82 days
Result: Improved the average daily weight gain (ADG) and feed efficiency of beef cattle.
Molecular Weight

1486.06

Formula

C66H101N17O16SZn
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@H](NC([C@@H](CCCN)NC([C@H](CCCCNC1=O)NC([C@H]([C@@H](C)CC)NC([C@@H](CCC([O-])=O)NC([C@@H](NC(C2CSC(C(C(CC)C)N)=N2)=O)CC(C)C)=O)=O)=O)=O)=O)[C@H](C)CC)N[C@@H](C(N[C@H](CC3=CN=CN3)C(N[C@H](CC([O-])=O)C(N[C@H]1CC(N)=O)=O)=O)=O)CC4=CC=CC=C4.[Zn+2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

1M HCl : 50 mg/mL (33.65 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6729 mL 3.3646 mL 6.7292 mL
5 mM 0.1346 mL 0.6729 mL 1.3458 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
1M HCl 1 mM 0.6729 mL 3.3646 mL 6.7292 mL 16.8230 mL
5 mM 0.1346 mL 0.6729 mL 1.3458 mL 3.3646 mL
10 mM 0.0673 mL 0.3365 mL 0.6729 mL 1.6823 mL
15 mM 0.0449 mL 0.2243 mL 0.4486 mL 1.1215 mL
20 mM 0.0336 mL 0.1682 mL 0.3365 mL 0.8412 mL
25 mM 0.0269 mL 0.1346 mL 0.2692 mL 0.6729 mL
30 mM 0.0224 mL 0.1122 mL 0.2243 mL 0.5608 mL
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Bacitracin Zinc Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bacitracin1405-89-6Zinc bacitracinBacterialAntibioticantibioticbroiler chickensproduction performanceInhibitorinhibitorinhibit

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