2. Cell Cycle/DNA Damage
  3. Deubiquitinase
  4. BC-1471

BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity.

For research use only. We do not sell to patients.

BC-1471 Chemical Structure

BC-1471 Chemical Structure

CAS No. : 896683-84-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 313 In-stock
Solution
10 mM * 1 mL in DMSO USD 313 In-stock
Solid
5 mg USD 280 In-stock
10 mg USD 420 In-stock
25 mg USD 720 In-stock
50 mg USD 1100 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

BC-1471 Related Antibodies

Top Publications Citing Use of Products

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USP1 USP2 USP7 USP8 USP30 UCHL1

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Description

BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity[1].

IC50 & Target

STAMBP[1]
Molecular Weight

508.63

Formula

C27H32N4O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC1OCCC1)CSC(N2CCC3=CC=CC=C3)=NC4=C(C=C(N5CCOCC5)C=C4)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (98.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9661 mL 9.8303 mL 19.6607 mL
5 mM 0.3932 mL 1.9661 mL 3.9321 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9661 mL 9.8303 mL 19.6607 mL 49.1516 mL
5 mM 0.3932 mL 1.9661 mL 3.9321 mL 9.8303 mL
10 mM 0.1966 mL 0.9830 mL 1.9661 mL 4.9152 mL
15 mM 0.1311 mL 0.6554 mL 1.3107 mL 3.2768 mL
20 mM 0.0983 mL 0.4915 mL 0.9830 mL 2.4576 mL
25 mM 0.0786 mL 0.3932 mL 0.7864 mL 1.9661 mL
30 mM 0.0655 mL 0.3277 mL 0.6554 mL 1.6384 mL
40 mM 0.0492 mL 0.2458 mL 0.4915 mL 1.2288 mL
50 mM 0.0393 mL 0.1966 mL 0.3932 mL 0.9830 mL
60 mM 0.0328 mL 0.1638 mL 0.3277 mL 0.8192 mL
80 mM 0.0246 mL 0.1229 mL 0.2458 mL 0.6144 mL
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BC-1471 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BC-1471896683-84-4BC1471BC 1471DeubiquitinaseDUBsNALP7IL-1βSTAMBPSTAM-binding proteinInhibitorinhibitorinhibit

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