1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. BChE-IN-19

BChE-IN-19 (Compound 7b) is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). BChE-IN-19 improves cholinergic scheduling in the nervous system. BChE-IN-19 can be used against Alzheimer's disease.

For research use only. We do not sell to patients.

BChE-IN-19 Chemical Structure

BChE-IN-19 Chemical Structure

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Description

BChE-IN-19 (Compound 7b) is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). BChE-IN-19 improves cholinergic scheduling in the nervous system. BChE-IN-19 can be used against Alzheimer's disease[1].

IC50 & Target

BChE

0.04 μM (IC50)

Molecular Weight

425.52

Formula

C25H31NO5

SMILES

O=C1C(CC2=CC=C(OCCCN3CCOCC3)C=C2)CC4=C1C=C(OC)C(OC)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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BChE-IN-19 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BChE-IN-19
Cat. No.:
HY-156031
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