2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. BChE-IN-22

BChE-IN-22 (compound 5A) is a selective eqBChE inhibitor (IC50: 0.53 μM), has anti-inflammatory and neuroprotective activities. BChE-IN-22 can inhibit cell damage caused by Aβ25-35 (HY-P0128) and improve cognitive dysfunction caused by Scopolamine (HY-N0296).

For research use only. We do not sell to patients.

BChE-IN-22 Chemical Structure

BChE-IN-22 Chemical Structure

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BChE-IN-22 Related Antibodies

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Description

BChE-IN-22 (compound 5A) is a selective eqBChE inhibitor (IC50: 0.53 μM), has anti-inflammatory and neuroprotective activities. BChE-IN-22 can inhibit cell damage caused by Aβ25-35 (HY-P0128) and improve cognitive dysfunction caused by Scopolamine (HY-N0296)[1].

IC50 & Target[1]

eqBCHE

0.53 μM (IC50)

Molecular Weight

453.53

Formula

C25H31N3O5
SMILES

CN(C(OC1=CC(OC(N(C)C)=O)=C(C=C1)C(N2CCC(CC2)CC3=CC=CC=C3)=O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BChE-IN-22 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BChE-IN-22Cholinesterase (ChE)Anti-inflammatory activityneuroprotective activityAlzheimer's diseaseInhibitorinhibitorinhibit

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HY-157384
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