1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. BChE-IN-5

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC50 of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease.

For research use only. We do not sell to patients.

BChE-IN-5 Chemical Structure

BChE-IN-5 Chemical Structure

CAS No. : 2983586-25-8

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Description

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC50 of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease[1].

IC50 & Target

AChE

 

BChE

 

In Vitro

BChE-IN-5 (compound 18) shows inhibitory potencies for hBChE and hAChE with IC50s of 2.8 nM, 16000 nM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

474.68

Formula

C30H42N4O

CAS No.
SMILES

O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BChE-IN-5
Cat. No.:
HY-143465
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