2. Inhibitory Antibodies
  3. Bentracimab

Bentracimab  (Synonyms: PB 2452; MEDI 2452)

Cat. No.: HY-P99469

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Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor (HY-1006) and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor.

For research use only. We do not sell to patients.

CAS No. : 2260568-31-6

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Bentracimab Related Antibodies

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Description

Bentracimab (PB 2452) is a neutralizing monoclonal antibody that binds Ticagrelor (HY-1006) and its major active circulating metabolite with high affinity. Bentracimab can rapidly reverse the antiplatelet effect of Ticagrelor[1].

Isotype

Fab-G1-lambda
Species

Human
In Vivo

Bentracimab‐bound Ticagrelor is primarily eliminated together with Bentracimab in the kidneys, and not recycled to the plasma[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS No.
SMILES

[Bentracimab]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Fab-G1-lambda
Purity & Documentation
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Bentracimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bentracimab2260568-31-6PB 2452 MEDI 2452PB2452PB-2452MEDI2452MEDI 2452MEDI-2452OthersTicagrelorantiplateletInhibitorinhibitorinhibit

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