2. Metabolic Enzyme/Protease Epigenetics Cell Cycle/DNA Damage
  3. Endogenous Metabolite PARP
  4. Benzamide-15N

Benzamide-15N  (Synonyms: Benzenecarboxamide-15N; Phenylamide-15N)

Cat. No.: HY-Z0283S Purity: ≥98.0%
COA Handling Instructions

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Benzamide-15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

For research use only. We do not sell to patients.

Benzamide-<sup>15</sup>N Chemical Structure

Benzamide-15N Chemical Structure

CAS No. : 31656-62-9

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10 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Benzamide-15N:

Benzamide-15N Related Antibodies

Top Publications Citing Use of Products

View All PARP Isoform Specific Products:

View All Isoforms
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

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Description

Benzamide-15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Benzamide-15N Related Antibodies
Molecular Weight

122.13

Formula

C7H715NO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([15NH2])C1=CC=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (818.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.1880 mL 40.9400 mL 81.8800 mL
5 mM 1.6376 mL 8.1880 mL 16.3760 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.1880 mL 40.9400 mL 81.8800 mL 204.6999 mL
5 mM 1.6376 mL 8.1880 mL 16.3760 mL 40.9400 mL
10 mM 0.8188 mL 4.0940 mL 8.1880 mL 20.4700 mL
15 mM 0.5459 mL 2.7293 mL 5.4587 mL 13.6467 mL
20 mM 0.4094 mL 2.0470 mL 4.0940 mL 10.2350 mL
25 mM 0.3275 mL 1.6376 mL 3.2752 mL 8.1880 mL
30 mM 0.2729 mL 1.3647 mL 2.7293 mL 6.8233 mL
40 mM 0.2047 mL 1.0235 mL 2.0470 mL 5.1175 mL
50 mM 0.1638 mL 0.8188 mL 1.6376 mL 4.0940 mL
60 mM 0.1365 mL 0.6823 mL 1.3647 mL 3.4117 mL
80 mM 0.1023 mL 0.5117 mL 1.0235 mL 2.5587 mL
100 mM 0.0819 mL 0.4094 mL 0.8188 mL 2.0470 mL
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Benzamide-15N Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzamide-15N31656-62-9Benzenecarboxamide-15NPhenylamide-15NEndogenous MetabolitePARPpoly ADP ribose polymeraseInhibitorinhibitorinhibit

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