2. Others Membrane Transporter/Ion Channel
  3. Isotope-Labeled Compounds Sodium Channel
  4. Benzocaine-d4

Benzocaine-d4 is the deuterium labeled Benzocaine. Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel, with an IC50 of 0.8 mM tested with a potential of +30 mV.

For research use only. We do not sell to patients.

Benzocaine-d<sub>4</sub> Chemical Structure

Benzocaine-d4 Chemical Structure

CAS No. : 342611-08-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Benzocaine-d4:

Benzocaine-d4 Related Antibodies

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  • Biological Activity

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Description

Benzocaine-d4 is the deuterium labeled Benzocaine. Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel, with an IC50 of 0.8 mM tested with a potential of +30 mV.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Benzocaine-d4 Related Antibodies
Molecular Weight

169.21

Formula

C9H7D4NO2
CAS No.
Unlabeled CAS

94-09-7
Appearance

Solid

Color

White to off-white

SMILES

CCOC(C1=C([2H])C([2H])=C(C([2H])=C1[2H])N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (590.98 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9098 mL 29.5491 mL 59.0982 mL
5 mM 1.1820 mL 5.9098 mL 11.8196 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.9098 mL 29.5491 mL 59.0982 mL 147.7454 mL
5 mM 1.1820 mL 5.9098 mL 11.8196 mL 29.5491 mL
10 mM 0.5910 mL 2.9549 mL 5.9098 mL 14.7745 mL
15 mM 0.3940 mL 1.9699 mL 3.9399 mL 9.8497 mL
20 mM 0.2955 mL 1.4775 mL 2.9549 mL 7.3873 mL
25 mM 0.2364 mL 1.1820 mL 2.3639 mL 5.9098 mL
30 mM 0.1970 mL 0.9850 mL 1.9699 mL 4.9248 mL
40 mM 0.1477 mL 0.7387 mL 1.4775 mL 3.6936 mL
50 mM 0.1182 mL 0.5910 mL 1.1820 mL 2.9549 mL
60 mM 0.0985 mL 0.4925 mL 0.9850 mL 2.4624 mL
80 mM 0.0739 mL 0.3694 mL 0.7387 mL 1.8468 mL
100 mM 0.0591 mL 0.2955 mL 0.5910 mL 1.4775 mL
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Benzocaine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzocaine-d4342611-08-9Isotope-Labeled CompoundsSodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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