2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. β-cyano-L-Alanine

β-cyano-L-Alanine  (Synonyms: Beta-cyano-l-alanine)

Cat. No.: HY-125773 Purity: ≥99.0%
SDS COA Handling Instructions

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β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.

For research use only. We do not sell to patients.

β-cyano-L-Alanine Chemical Structure

β-cyano-L-Alanine Chemical Structure

CAS No. : 6232-19-5

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50 mg USD 90 In-stock
100 mg USD 150 In-stock
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Based on 1 publication(s) in Google Scholar

β-cyano-L-Alanine Related Antibodies

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Description

β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates[1]. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury[2].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

β-cyano-L-Alanine (intraperitoneally; 50 mg/kg) abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult (postnatal age: 60 days) male C57BL/6J mice (25-30 g) gavage-fed with ethanol[2]
Dosage: 50 mg/kg
Administration: Intraperitoneally
Result: Abolished the protective effect of ethanol on cerebral I/R injury.
Molecular Weight

114.10

Formula

C4H6N2O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

N[C@@H](CC#N)C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 20.83 mg/mL (182.56 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.7642 mL 43.8212 mL 87.6424 mL
5 mM 1.7528 mL 8.7642 mL 17.5285 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (876.42 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

SDS (480 KB)

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.7642 mL 43.8212 mL 87.6424 mL 219.1061 mL
5 mM 1.7528 mL 8.7642 mL 17.5285 mL 43.8212 mL
10 mM 0.8764 mL 4.3821 mL 8.7642 mL 21.9106 mL
15 mM 0.5843 mL 2.9214 mL 5.8428 mL 14.6071 mL
20 mM 0.4382 mL 2.1911 mL 4.3821 mL 10.9553 mL
25 mM 0.3506 mL 1.7528 mL 3.5057 mL 8.7642 mL
30 mM 0.2921 mL 1.4607 mL 2.9214 mL 7.3035 mL
40 mM 0.2191 mL 1.0955 mL 2.1911 mL 5.4777 mL
50 mM 0.1753 mL 0.8764 mL 1.7528 mL 4.3821 mL
60 mM 0.1461 mL 0.7304 mL 1.4607 mL 3.6518 mL
80 mM 0.1096 mL 0.5478 mL 1.0955 mL 2.7388 mL
100 mM 0.0876 mL 0.4382 mL 0.8764 mL 2.1911 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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β-cyano-L-Alanine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-cyano-L-Alanine6232-19-5Beta-cyano-l-alanineEndogenous MetaboliteInhibitorinhibitorinhibit

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