2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Bicuculline (Standard)

Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice.

For research use only. We do not sell to patients.

Bicuculline (Standard) Chemical Structure

Bicuculline (Standard) Chemical Structure

CAS No. : 485-49-4

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Bicuculline (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bicuculline (Standard)485-49-4GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorconvulsantalkaloidcompetitiveneurotransmitterpotassiumSKAHPInhibitorinhibitorinhibit

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