Protein mono-ADP-ribosyltransferase PARP15

Definition:

Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Acts as a negative regulator of transcription.

References:

[1]. Sejal Vyas, et al. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nat Commun. 2014 Jul 21;5:4426. [Content Brief]

[2]. Tobias Karlberg, et al. Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein. J Biol Chem. 2015 Mar 20;290(12):7336-44. [Content Brief]

[3]. Ricardo C T Aguiar, et al. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. J Biol Chem. 2005 Oct 7;280(40):33756-65. [Content Brief]

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