2. Natural Products
  3. Plants Phenylpropanoids
  4. Thymelaeaceae Lignans
  5. Wikstroemia indica
  6. Bis-5,5-Nortrachelogenin

Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM.

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Bis-5,5-Nortrachelogenin Chemical Structure

Bis-5,5-Nortrachelogenin Chemical Structure

CAS No. : 870480-56-1

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Bis-5,5-Nortrachelogenin Related Antibodies

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Description

Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM[1].

Molecular Weight

746.75

Formula

C40H42O14
CAS No.
SMILES

OC1=C(OC)C=C(C[C@@H]2[C@](O)(C(OC2)=O)CC3=CC(OC)=C(C=C3)O)C=C1C4=CC(C[C@@H]5[C@](O)(C(OC5)=O)CC6=CC(OC)=C(C=C6)O)=CC(OC)=C4O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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Bis-5,5-Nortrachelogenin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis-5,5-Nortrachelogenin870480-56-1OthersBis-5,5-Nortrachelogenin 是从 Wikstroemia indica 根中分离得到的活性提取物。Bis-5,5-Nortrachelogenin 抑制脂多糖 (LPS) 和重组小鼠干扰素-γ (IFN-γ) 激活的小鼠巨噬细胞样细胞系 RAW 264.7 中一氧化氮 (NO) 的生成，IC50 值为 48.6 mM。Inhibitorinhibitorinhibit

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