2. Natural Products
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  4. Thymelaeaceae

Thymelaeaceae

 

Thymelaeaceae (81):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0281
    Daphnetin 486-35-1 99.86%
    Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1ß, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research.
    Daphnetin
  • HY-107421
    Prostratin 60857-08-1 99.80%
    Prostratin, a natural terpenoid compound, is a PKC activator, with a Ki of 12.5 nM and shows inhibitory effect on HIV-1.
    Prostratin
  • HY-N2963
    Broussonin E 90902-21-9 98.18%
    Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis.
    Broussonin E
  • HY-N0731
    Genkwanin 437-64-9 99.82%
    Genkwanin is a major non-glycosylated flavonoid with anti-flammatory activities.
    Genkwanin
  • HY-N1438
    Hydroxygenkwanin 20243-59-8 99.97%
    Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect.
    Hydroxygenkwanin
  • HY-N13121
    Daphnegiravone D 2581826-37-9
    Daphnegiravone D (compound 70) is an HDAC6 inhibitor with anti-hepatocellular carcinoma activity. Daphnegiravone D can induce apoptosis and selectively inhibit the proliferation of liver cancer cells through the p38 and JNK MAPK pathways.
    Daphnegiravone D
  • HY-N2681
    (±)-5'-Methoxylariciresinol 105256-12-0
    (±)-5'-Methoxylariciresinol is an ester-alcohol that can be isolated from Wikstroemia elliptica Merrill.
    (±)-5'-Methoxylariciresinol
  • HY-N0281R
    Daphnetin (Standard) 486-35-1
    Daphnetin (Standard) is the analytical standard of Daphnetin. This product is intended for research and analytical applications. Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1 , ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research.
    Daphnetin (Standard)
  • HY-N0699
    Daphnoretin 2034-69-7 99.83%
    Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity. Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst.
    Daphnoretin
  • HY-N7225
    Yuanhuacine 60195-70-2 99.47%
    Yuanhuacine (Gnidilatidin), a diterpene from Daphne genkwa, is an effective and highly selective inhibitor of the basal-like 2 (BL2) subtype of TNBC. Yuanhuacine can induce G2/M cell cycle arrest and has broad anti-tumor activity. Yuanhuacine is an orally active DNA damaging agent.
    Yuanhuacine
  • HY-N10093
    Chamaejasmine 69618-96-8 98.17%
    Chamaejasmine is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L. Chamaejasmine has antitumor activity. Chamaejasmine induces cell apoptosis, autophagy and ROS production, and activates the activity of AMPK/mTOR signal pathway.
    Chamaejasmine
  • HY-N1468
    Agarotetrol 69809-22-9 99.86%
    Agarotetrol is a chromone derivative isolated from Agarwood.
    Agarotetrol
  • HY-133181
    Triumbelletin 131559-54-1 ≥98.0%
    Triumbelletin is a tricoumarin rhamnopyranoside that can be found in Daphne mezereum.
    Triumbelletin
  • HY-W015616
    Benzylacetone 2550-26-7 99.93%
    Benzylacetone is an aromatic compound from agarwood. Benzylacetone exhibits potent and reversible antityrosinase (mushroom) activity， with IC50s of 2.8 mM and 0.6 mM for monophenolase and diphenolase, respectively. Benzylacetone has appetite-enhancing and locomotor-reducing effects.
    Benzylacetone
  • HY-111927
    Pilloin 32174-62-2 98.94%
    Pilloin, a flavonoid isolated from Marrubium cylleneum, exerts a cytotoxic action targeted at the transformed lymphoblasts. Pilloin also possesses anti-inflammatory activity.
    Pilloin
  • HY-121386
    Yuanhuanin 83133-14-6 99.27%
    Yuanhuanin is a natural product that originally recognized in D. sericea. Yuanhuanin also can be isolated also from D. koreana and D. pedunculata.
    Yuanhuanin
  • HY-N4010
    Iriflophenone 52591-10-3 98.07%
    Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation.
    Iriflophenone
  • HY-N7486
    Chamaejasmenin B 89595-71-1 ≥98.0%
    Chamaejasmenin B can be extracted from Stellera chamaejasme L. Chamaejasmenin B suppresses cancer cells migration and invasion. Chamaejasmenin B inhibits tumor metastasis. Chamaejasmenin B can be used in the research of cancers, such as breast cancers.
    Chamaejasmenin B
  • HY-N8220
    2-(2-Phenylethyl)chromone 61828-53-3 99.98%
    2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis.
    2-(2-Phenylethyl)chromone
  • HY-121597
    Yuankanin 77099-20-8
    Yuankanin is a genkwanin-5-bioside, the sugar moiety being composed of xylose and glucose. Yuankanin can be isolated from the methanol extract of the aerial parts of Gnidia involucrata (Thymelaeaceae).
    Yuankanin