Bis-PEG30-NHS ester

Cat. No.: HY-164724: FAQs
Data Sheet Handling Instructions

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Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Bis-PEG30-NHS ester Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

Molecular Weight

1633.81

Formula

C₇₂H₁₃₂N₂O₃₈

Appearance

Solid

SMILES

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (61.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.6121 mL	3.0603 mL	6.1207 mL
5 mM	0.1224 mL	0.6121 mL	1.2241 mL
10 mM	0.0612 mL	0.3060 mL	0.6121 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. John L. Magna, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.6121 mL	3.0603 mL	6.1207 mL	15.3017 mL
	5 mM	0.1224 mL	0.6121 mL	1.2241 mL	3.0603 mL
	10 mM	0.0612 mL	0.3060 mL	0.6121 mL	1.5302 mL
	15 mM	0.0408 mL	0.2040 mL	0.4080 mL	1.0201 mL
	20 mM	0.0306 mL	0.1530 mL	0.3060 mL	0.7651 mL
	25 mM	0.0245 mL	0.1224 mL	0.2448 mL	0.6121 mL
	30 mM	0.0204 mL	0.1020 mL	0.2040 mL	0.5101 mL
	40 mM	0.0153 mL	0.0765 mL	0.1530 mL	0.3825 mL
	50 mM	0.0122 mL	0.0612 mL	0.1224 mL	0.3060 mL
	60 mM	0.0102 mL	0.0510 mL	0.1020 mL	0.2550 mL