2. Apoptosis
  3. Apoptosis
  4. Bleomycin A5

Bleomycin A5  (Synonyms: Pingyangmycin)

Cat. No.: HY-N10470 Purity: 98.55%
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Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite.

For research use only. We do not sell to patients.

Bleomycin A5 Chemical Structure

Bleomycin A5 Chemical Structure

CAS No. : 11116-32-8

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5 mg USD 450 In-stock
10 mg USD 765 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Bleomycin A5:

Bleomycin A5 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Bleomycin A5

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  • Purity & Documentation

  • References

  • Customer Review

Description

Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite[1][2].

In Vitro

Bleomycin A5 (Pingyangmycin) can inhibit the growth of tumor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bleomycin A5 Related Antibodies
In Vivo

Bleomycin A5 (Pingyangmycin) (oral; 18 daily doses of 5 mg/kg) occurs anorexia, cachexia, skin ulcerations, and death and observes interstitial pneumonia, nephrosis and focal necrosis of the adrenal cortex[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1440.56

Formula

C57H89N19O21S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC1=NC(C2=NC(C(NCCCNCCCCN)=O)=CS2)=CS1)=O)=O)[C@@H](NC(C3=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C3C)=O)[C@H](C4=CN=CN4)O[C@H](O[C@H]5CO)[C@H]([C@H]([C@@H]5O)O)O[C@H](O[C@@H]6CO)[C@H]([C@H]([C@@H]6O)OC(N)=O)O
Structure Classification
Initial Source

Penicillium avellaneum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (69.42 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6942 mL 3.4709 mL 6.9417 mL
5 mM 0.1388 mL 0.6942 mL 1.3883 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6942 mL 3.4709 mL 6.9417 mL 17.3544 mL
5 mM 0.1388 mL 0.6942 mL 1.3883 mL 3.4709 mL
10 mM 0.0694 mL 0.3471 mL 0.6942 mL 1.7354 mL
15 mM 0.0463 mL 0.2314 mL 0.4628 mL 1.1570 mL
20 mM 0.0347 mL 0.1735 mL 0.3471 mL 0.8677 mL
25 mM 0.0278 mL 0.1388 mL 0.2777 mL 0.6942 mL
30 mM 0.0231 mL 0.1157 mL 0.2314 mL 0.5785 mL
40 mM 0.0174 mL 0.0868 mL 0.1735 mL 0.4339 mL
50 mM 0.0139 mL 0.0694 mL 0.1388 mL 0.3471 mL
60 mM 0.0116 mL 0.0578 mL 0.1157 mL 0.2892 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Bleomycin A5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bleomycin A511116-32-8PingyangmycinBleomycin A 5Bleomycin A-5ApoptosisglycopeptideantibioticantineoplasticapoptosisbacterialcancerInhibitorinhibitorinhibit

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