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  4. BM 15766 sulfate

BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase and reduces plasma cholesterol levels. BM 15766 sulfate is a hypolipidemic agent.

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BM 15766 sulfate Chemical Structure

BM 15766 sulfate Chemical Structure

CAS No. : 86621-94-5

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10 mg USD 675 In-stock
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BM 15766 sulfate Related Antibodies

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Description

BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase and reduces plasma cholesterol levels. BM 15766 sulfate is a hypolipidemic agent[1][2].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
500 nM
Compound: BM 15.766 sulfate
Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 24 hrs GC/MS analysis
Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 24 hrs GC/MS analysis
[PMID: 22882119]
Molecular Weight

482.98

Formula

C22H27ClN2O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(CCN2CCN(C/C=C/C3=CC=C(Cl)C=C3)CC2)C=C1.O=S(O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 2.6 mg/mL (5.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0705 mL 10.3524 mL 20.7048 mL
5 mM 0.4141 mL 2.0705 mL 4.1410 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0705 mL 10.3524 mL 20.7048 mL 51.7620 mL
5 mM 0.4141 mL 2.0705 mL 4.1410 mL 10.3524 mL
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BM 15766 sulfate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BM 1576686621-94-5BM15766BM-15766OthersCholesterolhypolipidemicInhibitorinhibitorinhibit

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