2. Anti-infection
  3. Bacterial
  4. BM635 mesylate

BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC50 of 0.6 μM against M. tuberculosis  H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635.

For research use only. We do not sell to patients.

BM635 mesylate Chemical Structure

BM635 mesylate Chemical Structure

CAS No. : 2703867-74-5

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BM635 mesylate Related Antibodies

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Description

BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC50 of 0.6 μM against M. tuberculosis  H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635[1].

IC50 & Target

MIC50: 0.08 μM (M. tuberculosis H37Rv)[1]
In Vivo

BM635 mesylate (oral administration; 50 mg/kg) results in gradual elevations in blood up to a Cmax of 2970 ng/ml with Tmax of 0.8 hour, it has a improved solubility compared to BM635 hydrochloride. In addition, BM635-Mes significantly improves the bioavailability with a AUC 4 times higher than free-base BM635[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

488.61

Formula

C26H33FN2O4S
CAS No.
SMILES

CC(C1=CC=C(C2=CC(CN3CCOCC3)=C(C)N2C4=CC=C(F)C=C4)C=C1)C.OS(=O)(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BM635 mesylate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BM6352703867-74-5BM 635BM-635Bacterialanti-mycobacterialM.tuberculosisMycobacteriumInhibitorinhibitorinhibit

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BM635 mesylate
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HY-109587B
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