2. JAK/STAT Signaling Metabolic Enzyme/Protease Cell Cycle/DNA Damage Stem Cell/Wnt Vitamin D Related/Nuclear Receptor
  3. STAT PPAR
  4. BML-260

BML-260 is a potent inhibitor of dual-specific phosphatases JSP-1 and DUSP22. BML-260 can activate UCP1 and thermogenesis in adipocytes in a JSP-1-independent manner. The effect of BML-260 on adipocytes is partially achieved through the activation of CREB, STAT3, and PPAR signaling pathways. BML-260 can be used in the research of inflammatory and proliferative disorders associated with JNK signaling dysfunction as well as obesity.

For research use only. We do not sell to patients.

BML-260 Chemical Structure

BML-260 Chemical Structure

CAS No. : 101439-76-3

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BML-260 Related Antibodies

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Description

BML-260 is a potent inhibitor of dual-specific phosphatases JSP-1 and DUSP22. BML-260 can activate UCP1 and thermogenesis in adipocytes in a JSP-1-independent manner. The effect of BML-260 on adipocytes is partially achieved through the activation of CREB, STAT3, and PPAR signaling pathways. BML-260 can be used in the research of inflammatory and proliferative disorders associated with JNK signaling dysfunction as well as obesity[1][2].

Molecular Weight

341.40

Formula

C17H11NO3S2
CAS No.
SMILES

O=C(O)C1=CC=C(N(C/2=O)C(SC2=C\C3=CC=CC=C3)=S)C=C1
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BML-260 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BML-260101439-76-3BML260BML 260STATPPARPeroxisome proliferator-activated receptorsinflammatoryproliferative disordersJSP-1obesityInhibitorinhibitorinhibit

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