2. GPCR/G Protein
  3. Adenylate Cyclase Prostaglandin Receptor
  4. BMY 45778

BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor.

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BMY 45778 Chemical Structure

BMY 45778 Chemical Structure

CAS No. : 152575-66-1

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Based on 1 publication(s) in Google Scholar

BMY 45778 Related Antibodies

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Description

BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor[1].

Molecular Weight

438.43

Formula

C26H18N2O5
CAS No.
SMILES

O=C(O)COC1=CC=CC(C2=C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)N=CO2)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BMY 45778 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMY 45778152575-66-1BMY45778BMY-45778Adenylate CyclaseProstaglandin ReceptorAdenylyl cyclaseplateletaggregationprostacyclin mimeticInhibitorinhibitorinhibit

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