Boc-Gln-Arg-Arg-AMC acetate

Cat. No.: HY-P4323A Purity: 98.41%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal.

For research use only. We do not sell to patients.

Boc-Gln-Arg-Arg-AMC acetate Chemical Structure

CAS No. : 2223665-74-3

Size	Price	Stock	Quantity
5 mg	USD 175	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of Boc-Gln-Arg-Arg-AMC acetate:

Boc-Gln-Arg-Arg-AMC Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

775.85

Formula

C₃₄H₅₃N₁₁O₁₀

CAS No.

2223665-74-3

Appearance

Solid

Color

White to off-white

Sequence

{Boc}-Gln-Arg-Arg-{AMC}

Sequence Shortening

{Boc}-QRR-{AMC}

SMILES

CC(O)=O.CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (128.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2889 mL	6.4445 mL	12.8891 mL
5 mM	0.2578 mL	1.2889 mL	2.5778 mL
10 mM	0.1289 mL	0.6445 mL	1.2889 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.41%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB) RP-HPLC (112 KB) MS (256 KB)

Handling Instructions (2659 KB)

References

[1]. Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.2889 mL	6.4445 mL	12.8891 mL	32.2227 mL
	5 mM	0.2578 mL	1.2889 mL	2.5778 mL	6.4445 mL
	10 mM	0.1289 mL	0.6445 mL	1.2889 mL	3.2223 mL
	15 mM	0.0859 mL	0.4296 mL	0.8593 mL	2.1482 mL
	20 mM	0.0644 mL	0.3222 mL	0.6445 mL	1.6111 mL
	25 mM	0.0516 mL	0.2578 mL	0.5156 mL	1.2889 mL
	30 mM	0.0430 mL	0.2148 mL	0.4296 mL	1.0741 mL
	40 mM	0.0322 mL	0.1611 mL	0.3222 mL	0.8056 mL
	50 mM	0.0258 mL	0.1289 mL	0.2578 mL	0.6445 mL
	60 mM	0.0215 mL	0.1074 mL	0.2148 mL	0.5370 mL
	80 mM	0.0161 mL	0.0806 mL	0.1611 mL	0.4028 mL
	100 mM	0.0129 mL	0.0644 mL	0.1289 mL	0.3222 mL