2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. Boeravinone B

Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress.

For research use only. We do not sell to patients.

Boeravinone B Chemical Structure

Boeravinone B Chemical Structure

CAS No. : 114567-34-9

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Boeravinone B Related Antibodies

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Description

Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress[1][2].

In Vitro

Boeravinone B is also active against a methicillin-resistant S. aureus (MRSA) strain, which showed a fourfold reduction in the ciprofloxacin MIC[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Boeravinone B Related Antibodies
Molecular Weight

312.27

Formula

C17H12O6
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(C(O)OC3=CC=CC=C32)OC4=CC(O)=C(C)C(O)=C14
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (160.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2024 mL 16.0118 mL 32.0236 mL
5 mM 0.6405 mL 3.2024 mL 6.4047 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Purity & Documentation

Purity: ≥97.0%

SDS (623 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2024 mL 16.0118 mL 32.0236 mL 80.0589 mL
5 mM 0.6405 mL 3.2024 mL 6.4047 mL 16.0118 mL
10 mM 0.3202 mL 1.6012 mL 3.2024 mL 8.0059 mL
15 mM 0.2135 mL 1.0675 mL 2.1349 mL 5.3373 mL
20 mM 0.1601 mL 0.8006 mL 1.6012 mL 4.0029 mL
25 mM 0.1281 mL 0.6405 mL 1.2809 mL 3.2024 mL
30 mM 0.1067 mL 0.5337 mL 1.0675 mL 2.6686 mL
40 mM 0.0801 mL 0.4003 mL 0.8006 mL 2.0015 mL
50 mM 0.0640 mL 0.3202 mL 0.6405 mL 1.6012 mL
60 mM 0.0534 mL 0.2669 mL 0.5337 mL 1.3343 mL
80 mM 0.0400 mL 0.2001 mL 0.4003 mL 1.0007 mL
100 mM 0.0320 mL 0.1601 mL 0.3202 mL 0.8006 mL
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Boeravinone B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boeravinone B114567-34-9P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243effluxpumpNorAMRSAInhibitorinhibitorinhibit

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