2. JAK/STAT Signaling Stem Cell/Wnt Apoptosis
  3. STAT Apoptosis
  4. BP-1-108

BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer.

For research use only. We do not sell to patients.

BP-1-108 Chemical Structure

BP-1-108 Chemical Structure

CAS No. : 1334492-85-1

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BP-1-108 Related Antibodies

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Description

BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer[1].

IC50 & Target[1]

STAT5

8.3 μM (Ki)

Molecular Weight

578.72

Formula

C32H38N2O6S
CAS No.
SMILES

O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(C)C=C(C)C=C4C)=O)=O)C=C1O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BP-1-108 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BP-1-1081334492-85-1STATApoptosisinhibitorphosphorylationleukemiaprostate cancerInhibitorinhibit

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