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  4. C-Laurdan

C-Laurdan is a fluorescent probe for imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan exhibits strong photostability under two-photon excitation and can be used for single and two-photon fluorescence imaging to detect lipid membrane properties such as membrane lateral organisation, various membrane-associated processes, etc.

For research use only. We do not sell to patients.

C-Laurdan Chemical Structure

C-Laurdan Chemical Structure

CAS No. : 959839-06-6

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Based on 1 publication(s) in Google Scholar

C-Laurdan Related Antibodies

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Description

C-Laurdan is a fluorescent probe for imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan exhibits strong photostability under two-photon excitation and can be used for single and two-photon fluorescence imaging to detect lipid membrane properties such as membrane lateral organisation, various membrane-associated processes, etc[1].

Molecular Weight

397.55

Formula

C25H35NO3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

Emission (Em)

490
Excitation (Ex)

440
SMILES

O=C(CN(C)C1=CC2=CC=C(C(CCCCCCCCCCC)=O)C=C2C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (125.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5154 mL 12.5770 mL 25.1541 mL
5 mM 0.5031 mL 2.5154 mL 5.0308 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5154 mL 12.5770 mL 25.1541 mL 62.8852 mL
5 mM 0.5031 mL 2.5154 mL 5.0308 mL 12.5770 mL
10 mM 0.2515 mL 1.2577 mL 2.5154 mL 6.2885 mL
15 mM 0.1677 mL 0.8385 mL 1.6769 mL 4.1923 mL
20 mM 0.1258 mL 0.6289 mL 1.2577 mL 3.1443 mL
25 mM 0.1006 mL 0.5031 mL 1.0062 mL 2.5154 mL
30 mM 0.0838 mL 0.4192 mL 0.8385 mL 2.0962 mL
40 mM 0.0629 mL 0.3144 mL 0.6289 mL 1.5721 mL
50 mM 0.0503 mL 0.2515 mL 0.5031 mL 1.2577 mL
60 mM 0.0419 mL 0.2096 mL 0.4192 mL 1.0481 mL
80 mM 0.0314 mL 0.1572 mL 0.3144 mL 0.7861 mL
100 mM 0.0252 mL 0.1258 mL 0.2515 mL 0.6289 mL
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C-Laurdan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C-Laurdan959839-06-6Fluorescent Dyefluorescent probelipidsingleo-photontwo-photonlateral organizationInhibitorinhibitorinhibit

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