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  4. C20 Sphingomyelin (d18:1/20:0)

C20 Sphingomyelin (d18:1/20:0)  (Synonyms: N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))

Cat. No.: HY-145549
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C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (HY-13753) and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

For research use only. We do not sell to patients.

C20 Sphingomyelin (d18:1/20:0) Chemical Structure

C20 Sphingomyelin (d18:1/20:0) Chemical Structure

CAS No. : 121999-68-6

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C20 Sphingomyelin (d18:1/20:0) Related Antibodies

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Description

C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (HY-13753) and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

Molecular Weight

759.13

Formula

C43H87N2O6P
CAS No.
SMILES

CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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C20 Sphingomyelin (d18:1/20:0) Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C20 Sphingomyelin (d18:1/20:0)121999-68-6N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine SM(d18:1/20:0)OthersInhibitorinhibitorinhibit

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