C5a Receptor agonist, W5Cha

Cat. No.: HY-P5506 Purity: 99.50%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC₅₀=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

C5a Receptor agonist, W5Cha Chemical Structure

CAS No. : 144555-23-7

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

867.13

Formula

C₄₅H₇₄N₁₀O₇

CAS No.

144555-23-7

Appearance

Solid

Color

White to off-white

Sequence

{N-me-Phe}-Lys-Pro-{d-Cha}-{Cha}-{d-Arg}

Sequence Shortening

{N-me-Phe}-KP-{d-Cha}-{Cha}-{d-Arg}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (115.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1532 mL	5.7661 mL	11.5323 mL
5 mM	0.2306 mL	1.1532 mL	2.3065 mL
10 mM	0.1153 mL	0.5766 mL	1.1532 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.50%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (255 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. DeMartino, et al. Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs. Journal of Biological Chemistry 270.27 (1995): 15966-15969. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1532 mL	5.7661 mL	11.5323 mL	28.8307 mL
	5 mM	0.2306 mL	1.1532 mL	2.3065 mL	5.7661 mL
	10 mM	0.1153 mL	0.5766 mL	1.1532 mL	2.8831 mL
	15 mM	0.0769 mL	0.3844 mL	0.7688 mL	1.9220 mL
	20 mM	0.0577 mL	0.2883 mL	0.5766 mL	1.4415 mL
	25 mM	0.0461 mL	0.2306 mL	0.4613 mL	1.1532 mL
	30 mM	0.0384 mL	0.1922 mL	0.3844 mL	0.9610 mL
	40 mM	0.0288 mL	0.1442 mL	0.2883 mL	0.7208 mL
	50 mM	0.0231 mL	0.1153 mL	0.2306 mL	0.5766 mL
	60 mM	0.0192 mL	0.0961 mL	0.1922 mL	0.4805 mL
	80 mM	0.0144 mL	0.0721 mL	0.1442 mL	0.3604 mL
	100 mM	0.0115 mL	0.0577 mL	0.1153 mL	0.2883 mL