Cabralealactone (Synonyms: Dipterocarpon)

Cat. No.: HY-N2979: FAQs
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Cabralealactone (Dipterocarpon) is a Alkaloids product that can be isolated from the root barks of Dictamnus dasycarpus..

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Cabralealactone Chemical Structure

CAS No. : 19865-87-3

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Description

Cabralealactone (Dipterocarpon) is a Alkaloids product that can be isolated from the root barks of Dictamnus dasycarpus.^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
786-0	IC₅₀	> 40 μM Compound: 13	Cytotoxicity against human 786-O cells after 72 hrs by MTT assay Cytotoxicity against human 786-O cells after 72 hrs by MTT assay	[PMID: 30106297]
A549	IC₅₀	> 40 μM Compound: 13	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30106297]
A549	IC₅₀	> 50 μM Compound: 18	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
COLO 205	IC₅₀	> 100 μM Compound: 14	Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay	[PMID: 17346076]
HeLa	IC₅₀	> 40 μM Compound: 13	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30106297]
HepG2	IC₅₀	> 40 μM Compound: 13	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30106297]
HepG2	IC₅₀	> 50 μM Compound: 18	Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
K562	IC₅₀	> 100 μM Compound: 14	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	> 100 μM Compound: 14	Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay	[PMID: 17346076]
K562/Adr	IC₅₀	> 100 μM Compound: 14	Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay	[PMID: 17346076]
KB	IC₅₀	63.5 μM Compound: 14	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 17346076]
MCF7	IC₅₀	> 50 μM Compound: 18	Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24547740]
MCF7	IC₅₀	97.9 μM Compound: 14	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 17346076]
RAW264.7	IC₅₀	> 100 μM Compound: 18	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay	[PMID: 24547740]

Molecular Weight

414.62

Formula

C₂₇H₄₂O₃

CAS No.

19865-87-3

SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(OC(CC4)=O)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

Cabralealactone Related Classifications

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Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cabralealactone19865-87-3DipterocarponOthersInhibitorinhibitorinhibit

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