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  5. Calcitonin gene-related peptide free acid

Calcitonin gene-related peptide free acid  (Synonyms: CGRP free acid)

Cat. No.: HY-P4058 Purity: 98.61%
SDS COA Handling Instructions Technical Support

Calcitonin gene-related peptide (CGRP) free acid is a neuropeptide. Calcitonin gene-related peptide can be used for the research of nociception, ingestive behaviour and modulation of the endocrine systems.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Calcitonin gene-related peptide free acid Chemical Structure

Calcitonin gene-related peptide free acid Chemical Structure

CAS No. : 83652-28-2

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1 mg In-stock
5 mg In-stock
10 mg In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Calcitonin gene-related peptide free acid Related Antibodies

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Description

Calcitonin gene-related peptide (CGRP) free acid is a neuropeptide. Calcitonin gene-related peptide can be used for the research of nociception, ingestive behaviour and modulation of the endocrine systems[1].

Clinical Trial
Molecular Weight

3790.31

Formula

C163H266N50O50S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe (Disulfide Cys2-Cys7)
Sequence Shortening

ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF (Disulfide Cys2-Cys7)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (26.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 25 mg/mL (6.60 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.2638 mL 1.3192 mL 2.6383 mL
5 mM 0.0528 mL 0.2638 mL 0.5277 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.2638 mL 1.3192 mL 2.6383 mL 6.5958 mL
5 mM 0.0528 mL 0.2638 mL 0.5277 mL 1.3192 mL
DMSO 10 mM 0.0264 mL 0.1319 mL 0.2638 mL 0.6596 mL
15 mM 0.0176 mL 0.0879 mL 0.1759 mL 0.4397 mL
20 mM 0.0132 mL 0.0660 mL 0.1319 mL 0.3298 mL
25 mM 0.0106 mL 0.0528 mL 0.1055 mL 0.2638 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Calcitonin gene-related peptide free acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Calcitonin gene-related peptide83652-28-2CGRPOthersneuropeptidenociceptioningestive behaviorendocrine systemsInhibitorinhibitorinhibit

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