2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Capeserod hydrochloride

Capeserod hydrochloride  (Synonyms: SL65.0155)

Cat. No.: HY-121249
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Capeserod hydrochloride (SL65.0155) is a 5-HT4(e) receptor partial agonist (Ki=0.6 nM) with potent cognitive enhancing properties. Capeserod hydrochloride acts as a partial agonist in cells expressing 5-HT4(b) and 5-HT4(e) splice variants, stimulating cAMP production with IC50 values ??of 244 and 29 nM, respectively. Capeserod hydrochloride is used in the study of memory impairment and dementia.

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Capeserod hydrochloride Chemical Structure

Capeserod hydrochloride Chemical Structure

CAS No. : 191023-43-5

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Capeserod hydrochloride Related Antibodies

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Description

Capeserod hydrochloride (SL65.0155) is a 5-HT4(e) receptor partial agonist (Ki=0.6 nM) with potent cognitive enhancing properties. Capeserod hydrochloride acts as a partial agonist in cells expressing 5-HT4(b) and 5-HT4(e) splice variants, stimulating cAMP production with IC50 values ??of 244 and 29 nM, respectively. Capeserod hydrochloride is used in the study of memory impairment and dementia[1].

IC50 & Target[1]

5-HT4(e) Receptor

0.6 nM (Ki)

Molecular Weight

493.38

Formula

C23H26Cl2N4O4
CAS No.
SMILES

O=C1OC(C2=C3OCCOC3=C(N)C(Cl)=C2)=NN1C4CCN(CC4)CCC5=CC=CC=C5.Cl
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Capeserod hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Capeserod191023-43-5SL65.01555-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorCognitive enhancementpartial agonistsplice variantmemory deficitInhibitorinhibitorinhibit

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