1246298-58-7

Chemical Structure

C24:1 1-Deoxyceramide (m18:1/24:1(15Z))
Synonym(s): C24:1(15Z) 1-Deoxyceramide; C24:1 Ceramide (m18:1/24:1(15Z)); Cer(m18:1/24:1(15Z))
CAS No: 1246298-58-7

Formula: C₄₂H₈₁NO₂

Molecular Weight: 632.10
IUPAC Name: (Z)-N-((2S,3R,E)-3-hydroxyoctadec-4-en-2-yl)tetracos-15-enamide
InChIKey: FZEIPTFJIHXKQL-OSHZVMBRSA-N
SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](C)NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O

Biological Activity: C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (C24:1(15Z) 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro^[1].

Cat. No.	Product Name	Purity	Description
HY-139283	C24:1 1-Deoxyceramide (m18:1/24:1(15Z))		C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) (C24:1(15Z) 1-Deoxyceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro.

References

[1]. Hannich JT, et al., Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. Acta Physiol (Oxf). 2021 May;232(1):e13610. [Content Brief]

Keywords:

C24:1 1-Deoxyceramide (m18:1/24:1(15Z))

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