2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 776-56-7

776-56-7

5-Fluoro-α-methyltryptamine hydrochloride Chemical Structure

776-56-7

Chemical Structure

  • 5-Fluoro-α-methyltryptamine hydrochloride
  • CAS No: 776-56-7
    Formula: C11H14ClFN2
    Molecular Weight: 228.69
  • IUPAC Name: 1-(5-fluoro-1H-indol-3-yl)propan-2-amine hydrochloride
  • InChIKey: RVHBLKWBRZWGLS-UHFFFAOYSA-N
  • SMILES: FC1=CC2=C(NC=C2CC(C)N)C=C1.Cl

Biological Activity: 5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively[1][2].

Cat. No. Product Name Purity Description
HY-W681014 5-Fluoro-α-methyltryptamine hydrochloride 5-Fluoro-α-methyltryptamine hydrochloride may cause an increase in intracellular levels of 5-HT followed by an increase in 5-HT release. 5-Fluoro-α-methyltryptamine hydrochloride exhibits EC50 values of 37 nM, 14 nM, 78 nM and 8.47 nM for DA, 5HT, NE and 5-HT2A, respectively.

References

[1]. N Chairungsrilerd, et al. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998 Mar;123(5):855-62. [Content Brief]
[2]. Bruce E Blough, et al. Alpha-ethyltryptamines as dual dopamine-serotonin releasers. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4754-4758. [Content Brief]

Keywords:

5-Fluoro-α-methyltryptamine hydrochloride