2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Cell Cycle/DNA Damage
  3. Endogenous Metabolite PPAR
  4. 566-58-5

566-58-5

5α-Pregnane-3α,20α-diol Chemical Structure

566-58-5

Chemical Structure

  • 5α-Pregnane-3α,20α-diol
  • Synonym(s): Allopregnanediol
  • CAS No: 566-58-5
    Formula: C21H36O2
    Molecular Weight: 320.51
  • IUPAC Name: (3R,5S,8R,9S,10S,13S,14S,17S)-17-((S)-1-hydroxyethyl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • InChIKey: YWYQTGBBEZQBGO-CGVINKDUSA-N
  • SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@H](O)C)C

Biological Activity: 5α-Pregnane-3α,20α-diol (Allopregnanediol) is a derivative of progesterone and is one of the various steroids secreted by the ovaries of rats. 5α-Pregnane-3α,20α-diol can significantly stimulate the release of luteinizing hormone (LH) in castrated rats that have been pre-treated with estrogen, while simultaneously inhibiting the secretion of follicle-stimulating hormone (FSH)[1].

Cat. No. Product Name Purity Description
HY-107850A 5α-Pregnane-3α,20α-diol 5α-Pregnane-3α,20α-diol (Allopregnanediol) is a derivative of progesterone and is one of the various steroids secreted by the ovaries of rats. 5α-Pregnane-3α,20α-diol can significantly stimulate the release of luteinizing hormone (LH) in castrated rats that have been pre-treated with estrogen, while simultaneously inhibiting the secretion of follicle-stimulating hormone (FSH).

References

[1]. M Zanisi, et al. Effects on gonadotropin secretion of 5-alpha-pregnane-3 alpha, 20 alpha-diol, a physiological progesterone derivative. Proc Soc Exp Biol Med. 1979 May;161(1):66-9. [Content Brief]

Keywords:

5α-Pregnane-3α,20α-diol