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165800-06-6

Zoledronic acid monohydrate Chemical Structure

165800-06-6

Chemical Structure

  • Zoledronic acid monohydrate
  • Synonym(s): Zoledronate monohydrate; CGP 42446 monohydrate; CGP42446A monohydrate; ZOL 446 monohydrate
  • CAS No: 165800-06-6
    Formula: C5H12N2O8P2
    Molecular Weight: 290.10
  • IUPAC Name: (1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl)bis(phosphonic acid) hydrate
  • InChIKey: FUXFIVRTGHOMSO-UHFFFAOYSA-N
  • SMILES: OC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1.[H]O[H]

Biological Activity: Zoledronic acid monohydrate (Zoledronate monohydrate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic acid monohydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic acid monohydrate also has anti-cancer effects[1].

Cat. No. Product Name Purity Description
HY-116097 PSB-1491 PSB-1491 is a selective and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 of 0.386 nM for hMAO-B. PSB-1491 shows >25000-fold selective versus MAO-A.

References

[1]. Lianwei Wang, et al. Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review. BMC Cancer. 2020; 20: 1059. [Content Brief]

Keywords:

Zoledronic acid monohydrateZoledronic acid (monohydrate) (Standard)