2. Others
  3. Isotope-Labeled Compounds
  4. 1834610-73-9

1834610-73-9

PF-06456384 Chemical Structure

1834610-73-9

Chemical Structure

  • PF-06456384
  • CAS No: 1834610-73-9
    Formula: C35H32F3N7O3S2
    Molecular Weight: 719.80
  • IUPAC Name: 3-cyano-4-((3-(2-(((2-(piperidin-4-yl)ethyl)amino)methyl)pyridin-4-yl)-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)oxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
  • InChIKey: WSPHMGORSRQULF-UHFFFAOYSA-N
  • SMILES: N#CC1=CC(S(=O)(NC2=NC=NS2)=O)=CC=C1OC3=CC=C(C4=CC(C(F)(F)F)=CC=C4)C=C3C5=CC(CNCCC6CCNCC6)=NC=C5

Biological Activity: PF-06456384 is a highly potent and selective NaV1.7 inhibitor with an IC50 of 0.01 nM. PF-06456384 has the potential for formalin pain model research[1].

Cat. No. Product Name Purity Description
HY-118952 PF-06456384 PF-06456384 is a highly potent and selective NaV1.7 inhibitor with an IC50 of 0.01 nM. PF-06456384 has the potential for formalin pain model research.

References

[1]. R Ian Storer, et al. Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4805-4811. [Content Brief]

Keywords:

PF-06456384