2. Stem Cell/Wnt
  3. Wnt β-catenin
  4. 1219439-82-3

1219439-82-3

PTK7/β-catenin-IN-6 Chemical Structure

1219439-82-3

Chemical Structure

  • PTK7/β-catenin-IN-6
  • CAS No: 1219439-82-3
    Formula: C25H19Cl2N3O3
    Molecular Weight: 480.34
  • InChIKey: VZIQATUWSFFKSJ-JLHYYAGUSA-N
  • SMILES: O=C(N1C2=C(NC(C1CC(NC3=CC=C(C(Cl)=C3)Cl)=O)=O)C=CC=C2)/C=C/C4=CC=CC=C4

Biological Activity: PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC)[1].

Cat. No. Product Name Purity Description
HY-160493 PTK7/β-catenin-IN-6 PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC).

References

[1]. Ganier L, et al., Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS Chem Biol. 2022 May 20;17(5):1061-1072. [Content Brief]

Keywords:

PTK7/β-catenin-IN-6