2. Stem Cell/Wnt
  3. Wnt β-catenin
  4. 152-53-4

152-53-4

Cycloguanil hydrochloride Chemical Structure

152-53-4

Chemical Structure

  • Cycloguanil hydrochloride
  • CAS No: 152-53-4
    Formula: C11H15Cl2N5
    Molecular Weight: 288.18
  • IUPAC Name: 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride
  • InChIKey: MOUAPRKJJUXEIE-UHFFFAOYSA-N
  • SMILES: NC1=NC(N)=NC(C)(N1C2=CC=C(C=C2)Cl)C.[H]Cl

Biological Activity: Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].

Cat. No. Product Name Purity Description
HY-12784AR Cycloguanil (hydrochloride) (Standard) ≥98% Cycloguanil (hydrochloride) (Standard) is the analytical standard of Cycloguanil (hydrochloride). This product is intended for research and analytical applications. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
HY-12784A Cycloguanil hydrochloride 99.93% Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
HY-12784AS1 Cycloguanil-d6 hydrochloride Cycloguanil-d6 hydrochloride is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
HY-12784AS Cycloguanil-d4 hydrochloride Cycloguanil-d4 (hydrochloride) is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.

References

[1]. Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200. [Content Brief]

Keywords:

Cycloguanil (hydrochloride) (Standard)Cycloguanil hydrochlorideCycloguanil-d6 hydrochlorideCycloguanil-d4 hydrochloride