2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. 1257323-84-4

1257323-84-4

NPEC-caged-(S)-AMPA Chemical Structure

1257323-84-4

Chemical Structure

  • NPEC-caged-(S)-AMPA
  • CAS No: 1257323-84-4
    Formula: C16H17N3O8
    Molecular Weight: 379.32
  • IUPAC Name: (2S)-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)-2-(((1-(2-nitrophenyl)ethoxy)carbonyl)amino)propanoic acid
  • InChIKey: LGVJRWDYNJZRRP-MYIOLCAUSA-N
  • SMILES: O=C1C(C[C@@H](C(O)=O)NC(OC(C2=C(C=CC=C2)[N+]([O-])=O)C)=O)=C(C)ON1

Biological Activity: NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor[1].

Cat. No. Product Name Purity Description
HY-103235 NPEC-caged-(S)-AMPA NPEC- caged-(S)-AMPA, a caged neurotransmitter analog, is a NPEC photoprotecting group caged the (S)-AMPA (HY-100815A) to make caged ligands specific for glutamate receptor sub-types. NPEC- caged-(S)-AMPA selectively activates AMPA receptor.

References

[1]. Francisco Palma-Cerda, et al. New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 2012 Sep;63(4):624-34. [Content Brief]

Keywords:

NPEC-caged-(S)-AMPA