2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. 126876-64-0

126876-64-0

Naltrindole 5′-isothiocyanate Chemical Structure

126876-64-0

Chemical Structure

  • Naltrindole 5′-isothiocyanate
  • Synonym(s): 5'-NTII
  • CAS No: 126876-64-0
    Formula: C27H25N3O3S
    Molecular Weight: 471.57
  • SMILES: O[C@@]12[C@@]([C@](O3)([H])C(NC4=CC=C5N=C=S)=C(C4=C5)C2)(CC6)C(C3=C7O)=C(C=C7)C[C@@]1([H])N6CC8CC8

Biological Activity: Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET (HY-P1332) without affecting the analgesic effects induced by DPDPE (HY-P1334)[1].

Cat. No. Product Name Purity Description
HY-172149 Naltrindole 5′-isothiocyanate Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET (HY-P1332) without affecting the analgesic effects induced by DPDPE (HY-P1334).

References

[1]. S Chakrabarti, et al. Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice. Life Sci. 1993;53(23):1761-5. [Content Brief]

Keywords:

Naltrindole 5′-isothiocyanate