2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Autophagy Apoptosis
  3. RAR/RXR Autophagy Apoptosis
  4. 623-58-5

623-58-5

Acetoacetic acid sodium Chemical Structure

623-58-5

Chemical Structure

  • Acetoacetic acid sodium
  • CAS No: 623-58-5
    Formula: C4H5NaO3
    Molecular Weight: 124.07
  • IUPAC Name: sodium 3-oxobutanoate
  • InChIKey: UAKCMIIOSJFOTD-UHFFFAOYSA-M
  • SMILES: CC(CC(O[Na])=O)=O

Biological Activity: Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases[1][2][3].

Cat. No. Product Name Purity Description
HY-112540B Acetoacetic acid sodium ≥98.0% Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases.

References

[1]. Shi X, et al. Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. J Dairy Res. 2016 Nov;83(4):442-446. [Content Brief]

Keywords:

Acetoacetic acid sodium