2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. 149882-10-0

149882-10-0

Lurtotecan Chemical Structure

149882-10-0

Chemical Structure

  • Lurtotecan
  • Synonym(s): GI147211; OSI-211
  • CAS No: 149882-10-0
    Formula: C28H30N4O6
    Molecular Weight: 518.56
  • IUPAC Name: (S)-8-ethyl-8-hydroxy-15-((4-methylpiperazin-1-yl)methyl)-2,3,11,14-tetrahydro-12H-[1,4]dioxino[2,3-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12(8H)-dione
  • InChIKey: RVFGKBWWUQOIOU-NDEPHWFRSA-N
  • SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CN5CCN(C)CC5)C6=CC(OCCO7)=C7C=C6N=C4C3=C2)=O

Biological Activity: Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].

Cat. No. Product Name Purity Description
HY-13670 Lurtotecan 98.01% Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects.

References

[1]. D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9. [Content Brief]

Keywords:

Lurtotecan