2. PI3K/Akt/mTOR Anti-infection
  3. PI4K Parasite
  4. 1513879-19-0

1513879-19-0

KDU691 Chemical Structure

1513879-19-0

Chemical Structure

  • KDU691
  • CAS No: 1513879-19-0
    Formula: C22H18ClN5O2
    Molecular Weight: 419.86
  • IUPAC Name: N-(4-chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide
  • InChIKey: TYMFFISSODJRDV-UHFFFAOYSA-N
  • SMILES: ClC1=CC=C(N(C(C2=CN3C(C=N2)=NC=C3C4=CC=C(C(NC)=O)C=C4)=O)C)C=C1

Biological Activity: KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites[1].

Cat. No. Product Name Purity Description
HY-12912 KDU691 99.42% KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.

References

[1]. Dembele L, et al. The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Sci Rep. 2017;7(1):2325. Published 2017 May 24. [Content Brief]

Keywords:

KDU691