2. Anti-infection
  3. HCV SARS-CoV
  4. 2050041-12-6

2050041-12-6

Ledipasvir-d<sub>6</sub> Chemical Structure

2050041-12-6

Chemical Structure

  • Ledipasvir-d6
  • Synonym(s): GS-5885-d6
  • CAS No: 2050041-12-6
    Formula: C49H48D6F2N8O6
    Molecular Weight: 895.04
  • IUPAC Name: methyl-d3 ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-(((methoxy-d3)carbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
  • InChIKey: VRTWBAAJJOHBQU-NEKIOSTPSA-N
  • SMILES: O=C(OC([2H])([2H])[2H])N[C@H](C(N([C@H](C1=NC=C(C2=CC(C(F)(F)C3=C4C=CC(C5=CC=C6N=C([C@H]7N(C([C@@H](NC(OC([2H])([2H])[2H])=O)C(C)C)=O)[C@]8([H])CC[C@@]7([H])C8)NC6=C5)=C3)=C4C=C2)N1)C9)CC%109CC%10)=O)C(C)C

Biological Activity: Ledipasvir-d6 is the deuterium labeled Ledipasvir. Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A, with EC50s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.62 μM[3].

Cat. No. Product Name Purity Description
HY-15602S Ledipasvir-d6 ≥99.0% Ledipasvir-d6 is the deuterium labeled Ledipasvir. Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A, with EC50s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.62 μM.
HY-15602 Ledipasvir 99.68% Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A, with EC50s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.62 μM.

Keywords:

Ledipasvir-d6Ledipasvir