2. PROTAC
  3. PROTAC Linkers
  4. 2499491-04-0

2499491-04-0

STAT3-IN-10 Chemical Structure

2499491-04-0

Chemical Structure

  • STAT3-IN-10
  • CAS No: 2499491-04-0
    Formula: C17H13NO5
    Molecular Weight: 311.29
  • IUPAC Name: 2-acetyl-6-((4-methoxyphenyl)amino)benzofuran-4,7-dione
  • InChIKey: DKMJDBDFJFQKNU-UHFFFAOYSA-N
  • SMILES: COC(C=C1)=CC=C1NC2=CC(C3=C(C2=O)OC(C(C)=O)=C3)=O

Biological Activity: STAT3-IN-10 is a STAT3 inhibitor with an IC50 value of 5.18 µM. STAT3-IN-10 directly binds to STAT3 SH2 domain, induces cancer cells apoptosis[1].

Cat. No. Product Name Purity Description
HY-146728 STAT3-IN-10 STAT3-IN-10 is a STAT3 inhibitor with an IC50 value of 5.18 µM. STAT3-IN-10 directly binds to STAT3 SH2 domain, induces cancer cells apoptosis.

References

[1]. Kai-Rui Feng, et al. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy. Eur J Med Chem. 2020 Sep 1;201:112428. [Content Brief]

Keywords:

STAT3-IN-10