2. Anti-infection
  3. Parasite
  4. 2368253-58-9

2368253-58-9

CWHM-1552 Chemical Structure

2368253-58-9

Chemical Structure

  • CWHM-1552
  • CAS No: 2368253-58-9
    Formula: C22H27F2N3O
    Molecular Weight: 387.47
  • IUPAC Name: N-((3S,4R)-4-(4-(1,1-difluoroethyl)phenyl)pyrrolidin-3-yl)-2-(4-(dimethylamino)phenyl)acetamide
  • InChIKey: WQTOGFREMHSJJS-VQTJNVASSA-N
  • SMILES: CN(C)C1=CC=C(CC(N[C@@H]2CNC[C@H]2C3=CC=C(C(F)(C)F)C=C3)=O)C=C1

Biological Activity: CWHM-1552 is an orally efficacious inhibitor of P. falciparum with IC50s of 51 nM and 53 nM for 3D7 and Dd2 strain, respectively[1].

Cat. No. Product Name Purity Description
HY-128354 CWHM-1552 CWHM-1552 is an orally efficacious inhibitor of P. falciparum with IC50s of 51 nM and 53 nM for 3D7 and Dd2 strain, respectively.

References

[1]. Meyers MJ, et al. 4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N-(4-arylpyrrolidin-3-yl) acetamides. ACS Med Chem Lett. 2019 May, 10(6):966-971. [Content Brief]

Keywords:

CWHM-1552