2. Apoptosis Immunology/Inflammation
  3. Survivin COX TNF Receptor Apoptosis
  4. 24150-24-1

24150-24-1

Terameprocol Chemical Structure

24150-24-1

Chemical Structure

  • Terameprocol
  • Synonym(s): EM-1421
  • CAS No: 24150-24-1
    Formula: C22H30O4
    Molecular Weight: 358.47
  • IUPAC Name: 4,4'-((2R,3S)-2,3-dimethylbutane-1,4-diyl)bis(1,2-dimethoxybenzene)
  • InChIKey: ORQFDHFZSMXRLM-IYBDPMFKSA-N
  • SMILES: COC1=CC(C[C@H](C)[C@H](C)CC2=CC=C(OC)C(OC)=C2)=CC=C1OC

Biological Activity: Terameprocol is an inhibitor targeting the Sp1 transcription factor, which can selectively inhibit the transcription of Sp1-dependent genes. Terameprocol exerts its effects by inhibiting Sp1-mediated gene transcription, such as reducing the expression of genes like CDC2, survivin and HMGB1, thereby arresting the cell cycle, inducing apoptosis, and suppressing the inflammatory response. Terameprocol exhibits anti-proliferative, pro-apoptotic, and anti-inflammatory activities and is currently mainly used in the research of diseases such as cancer and pulmonary arterial hypertension[1][2][3].

Cat. No. Product Name Purity Description
HY-10447 Terameprocol 99.33% Terameprocol is an inhibitor targeting the Sp1 transcription factor, which can selectively inhibit the transcription of Sp1-dependent genes. Terameprocol exerts its effects by inhibiting Sp1-mediated gene transcription, such as reducing the expression of genes like CDC2, survivin and HMGB1, thereby arresting the cell cycle, inducing apoptosis, and suppressing the inflammatory response. Terameprocol exhibits anti-proliferative, pro-apoptotic, and anti-inflammatory activities and is currently mainly used in the research of diseases such as cancer and pulmonary arterial hypertension.

Keywords:

Terameprocol