2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 256224-04-1

256224-04-1

N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine Chemical Structure

256224-04-1

Chemical Structure

  • N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine
  • CAS No: 256224-04-1
    Formula: C17H25N5O7
    Molecular Weight: 411.41
  • IUPAC Name: N-(9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
  • InChIKey: MDFNPXKMEUCWGJ-UBEDBUPSSA-N
  • SMILES: OC[C@@H]1[C@@H](OCCOC)[C@@H](O)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O1

Biological Activity: N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Cat. No. Product Name Purity Description
HY-154547 N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).

References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. [Content Brief]

Keywords:

N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine